Peyronie's disease - causes of the disease, symptoms, stages of development, diagnosis and treatment in Moscow

Worried about curvature of the penis and pain during erection? It is possible that you have Peyronie's disease, which is treated in Moscow at the "K+31" multidisciplinary clinic. We guarantee complete confidentiality. Information about this delicate issue will never get to outsiders.

What is Peyronie's disease?

Plastic induration of the penis (known as Peyronie's syndrome or Van Buren's syndrome) is an overgrowth of connective tissue in the membrane of the cavernous bodies. The pathological process leads to contracture of the fascia and flexion of the penis during arousal. The etiology of this disease is not yet clear. The likely cause is infectious or non-infectious inflammation.

Predisposing factors:

  • microtrauma during sexual intercourse (for example, with a lack of lubrication);
  • vascular disease (vein thrombosis, atherosclerosis);
  • hypovitaminosis A and E;
  • history of catheterization or douching;
  • diseases with metabolic disorders (diabetes, gouty arthritis);
  • an autoimmune process that destroys protein tissue;
  • scleroderma;
  • myopathy.

Please note: The prevalence of the disease can be as high as 10%. Most of the patients are between 50 and 60 years of age. In 16% of cases, pathology is detected by chance during an examination by a urologist or andrologist.

Peyronie's disease is detected only in adult men who are sexually active. The diagnosis is based on the history and comprehensive clinical examination.

Main symptoms:

  1. anatomical deformity;
  2. pain during erection;
  3. erectile dysfunction.

A scarring change in the connective tissue membrane (penile fibromatosis) causes a curvature of the penis during an erection. Deviation is accompanied by pain and interferes with sexual intercourse. In some cases, fibrotic changes can progress and spread inside the cavernous bodies, preventing their distal sections from filling with blood.

In the development of penile fibrosis, 2 clear clinical phases can be distinguished.

The acute stage is characterized by inflammation and pain. Its duration is approximately six months. At this stage, a knot of dense elastic consistency is formed. Patients often take it for a tumor, and it is for this reason that they go to the doctor.

In the chronic phase of Peyronie's syndrome, fibrotic changes first progress and then stabilize. The duration of this stage is from 7 months. up to a year and a half. The plaques thicken, calcium salts are deposited in them, and the pain may disappear.

Further, in 13% of cases, spontaneous remission occurs, but in most patients, the deformation leads to a decrease in the length of the penis and erectile dysfunction.

Diagnosis, treatment and prevention of Peyronie's disease

First of all, the specialist collects a detailed history. The doctor needs to know how long the problems started.

Examination

During the examination, the doctor determines the degree of curvature of the penis, as well as the number, diameter and localization of fibrous formations. The presence of fibrous foci in the cavernous bodies or the septum between them leads to problems with erection and shortening of the organ when aroused.

It is possible to detect fibrotic changes in the tunica albuginea during an ultrasound scan of an erect organ. In 70% of cases, fibrous plaques can be detected by palpation.

The best way to visualize structural changes is Doppler ultrasound. If dense and large calcified masses are detected, surgical intervention is likely to be required. Duplex scanning allows assessing local blood flow.

In addition, radiography (cavernosography) and magnetic resonance imaging are performed with a preliminary injection of a contrast agent.

How to cure Peyronie's disease?

When this pathology is detected, complex treatment is required. Pharmacotherapy involves the appointment of potassium paraaminobenzoate, tocopherol (vit. E) and carnitine. These active substances are part of the combined Peyroflex.

Important: Sometimes the pathology disappears by itself after a few months. Mild forms of the disease that do not interfere with full sexual contact do not require correction.

Local injections of collagenase, corticosteroid hormones and a calcium channel blocker (verapamil) help to achieve a good effect.

In addition, radio or ultrasound therapy may be prescribed. Ultrasound stimulates microcirculation and stops scarring. Irradiation relieves pain, but adverse effects on healthy tissues are not excluded.

If conservative measures are ineffective, they resort to surgical correction (phalloplasty).

Indications for surgery:

  1. complex deviations (in the form of a screw or hourglass);
  2. warp >30˚;
  3. impotence;
  4. congenital anatomical disorders.

During the intervention, fibrous plaques are excised, and the resulting defect is replaced with an autograft. In severe cases, intracavernous splinting is indicated. Prosthetics using an erector or replacement of the cavernous bodies with inflatable balloons or solid rods may be needed.

Prevention of cavernous fibrosis

To prevent the development of this disease, men are advised to take measures to protect the phallus from injury during sexual intercourse, sports and other vigorous activities.

You can undergo complex treatment of Peyronie's b-nib at the medical center "K+31". The clinic has modern diagnostic equipment and its own laboratory. Doctors of the highest category work for us: they apply the latest achievements of medical science in practice.

The quality of our work is evidenced by the numerous reviews of grateful patients left on the clinic's website. If symptoms of the disease appear, do not waste precious time on self-treatment, but make an appointment with our urologists.

In our medical center, low prices for the services of highly specialized specialists are set. Promotions are regularly held and there is a loyalty program for regular customers.

Service record

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Specialists

All specialists
Rasner
Pavel Ilyich

Consultant in urology, urologist

Doctor of Sciences, PhD, professor

Osmolovsky
Boris Evgenyevich

Head of the Department of Urology, Urologist

PhD

Tereshchenko
Suren Alexandrovich

Doctor urologist-andrologist

Doctor of Sciences, PhD

Kamalov
Armais Albertovich

Chief Consultant in Urology, Urologist

Academician, professor, Doctor of Sciences, PhD

Pshikhachev
Ahmed Mukhamedovich

Urologist, Oncologist

Doctor of Sciences, PhD

Gomberg
Mikhail Alexandrovich

Dermatovenereologist

Doctor of Sciences, PhD, professor

Marchenko
Vladimir Vladimirovich

Leading urologist-andrologist, urogynecologist, pelvic pain specialist