Bone tumors and metastases in the spine

Bone tumor is a collective name for malignant and benign tumors that affect skeletal bone tissue (bone or cartilage). Malignant bone tumors are called sarcomas. Most often it is osteosarcoma or osteoma. In some cases, the term is applicable to secondary lesions caused by metastases. Bone tumors occur in patients of any age and regardless of gender. Our clinic provides diagnostics and treatment of bone cancer and other neoplasms of bone or cartilage tissues.

The main types of bone cancer are:

  • Osteosarcoma is a primary bone cancer, the most common type, and most often occurs in young people (usually males) from 10 to 30 years old. Malignant bone tumors of this type usually affect the bone tissue of the extremities and pelvic bones. Treatment consists of a course of chemotherapy before surgical removal of the tumor.
  • Chondrosarcoma is also a common primary bone cancer, the risk of which increases with age and does not depend on gender. But in young people under 20, in children and adolescents, such bone tumors are very rare. They affect the limbs, pelvic bones, bones of the skull or shoulder blades. It is sometimes found in internal organs, such as the trachea or larynx, which contain areas of cartilage. Treatment is mainly surgical.
  • Ewing's sarcoma is a bone cancer that, on the contrary, is more common in children and young people under 30 years of age. In older people, these malignant bone tumors are much less common. This bone sarcoma forms in the bones of the arms and legs, pelvis, shoulder blades, ribs. The treatment uses an integrated approach and a combination of various methods.
  • Metastatic bone cancer - bone metastases that have arisen against the background of oncological diseases of other organs: prostate, breast, stomach, lung. Depending on the organ in which the cancer originally arose, it is called so, for example, breast cancer with metastases. Metastatic bone cancer is the most common cancer that affects the bones. Treatment depends on the type of primary cancer.
  • Malignant fibrous histiocytoma is a bone cancer of the elderly and middle-aged people that usually affects the soft tissues, but in rare cases the tumor can be localized in the tissues of the bones of the skeleton. In the latter case, it occurs in the lower extremities, in the knee area. Sometimes a bone tumor can metastasize to other organs, such as the lungs.
  • Fibrosarcoma is also a soft tissue cancer, but in some cases it affects the bones of the extremities. It occurs mainly in adults and the elderly. The treatment is specific.
  • Chordoma is a bone cancer that is localized in the spine or at the base of the skull, more often in men over the age of 30 years. This malignant bone tumor has a slow and local growth and rarely metastasizes to the liver and lymph nodes. Treatment in most cases is surgical.

Other bone cancers: chondroma, osteochondroma, osteoma, osteoblastoma, etc.

Stages of bone cancer:

  • Stage 1 - characterized by the absence of distant metastases and local localization of a malignant bone tumor. The tumor is low aggressive.
  • Stage 2 - localization does not change, there are no metastases yet, but the aggressiveness of the bone tumor is increasing.
  • Stage 3 - other foci of disease appear in the bone.
  • Stage 4 - bone tumor gives metastases to other organs and tissues.

Causes of bone tumors

The causes of tumors in the bone tissue and bone cancer are not fully understood, but some risk factors are known:

  • radiotherapy and chemotherapy given for other types of cancer may be associated with an increased risk of osteosarcoma;
  • metal fixation devices used for fractures also increase the risk of developing osteosarcoma;
  • some hereditary diseases, such as retinoblastoma or Li-Fraumeni syndrome, increase the risk of bone cancer;
  • Another risk factor is Paget's disease, which manifests itself in old age.

Symptoms of a bone tumor

In the early stages, a malignant bone tumor may not manifest itself, the disease is asymptomatic. Early bone cancer can only be detected during a routine medical examination. According to statistics, the tubular bones of the upper or lower extremities, the pelvis, and the skull are more often affected. The patient can be diagnosed with myeloma, chondrosarcoma, chordoma, hemangioendothelioma.

Among the symptoms and signs of bone tumor progression:

  • severe pain in the affected bone, which may occur or intensify at night, the pain may radiate to another part of the body - for example, from the arm to the shoulder blade;
  • characterized by numbness or tingling in the affected part;
  • loss of muscle strength, paralysis;
  • thinning of the bones, which increases the risk of a pathological fracture in the bone;
  • limitation of the motor function of the affected joint;
  • growths, bulges or bumps on the body.

Pain is the result of pinched nerves due to bone cancer. Over time, the development of a malignant bone tumor causes intoxication of the body. It is manifested by nausea, vomiting, weakness, frequent dizziness. If the tumor is palpated through the skin, then it seems immobile and does not have clearly defined boundaries.

Diagnosis of bone tumors

Accurate diagnosis of bone tumors is very important for choosing further treatment. To diagnose bone cancer, the patient is sent for an X-ray examination, as this is the most accessible diagnostic tool and very fast. Radiography should be performed in two projections. With this approach, the localization of the bone tumor will be clearly visible on the obtained images. According to radiographs, you can assess the condition of the bone, detect formations and bone tumors, metastases.

At the same time, CT scan and bone scintigraphy are mandatory. With the help of computed tomography, the doctor can accurately determine the extent of the spread of the neoplasm and the presence of bone cancer metastases, the exact size of the bone tumor, the number of foci, etc. Bone scintigraphy is used to visually display the mineralization of the bone tissue of the skeleton. The procedure involves the introduction of a radioisotope. Magnetic resonance imaging allows you to examine the soft tissues surrounding the bone tumor and their condition. Positron emission tomography finds small metastases of bone cancer, but for this you need to take a special substance with a radioactive label, due to which tumor cells become visible.

However, only a biopsy can say for sure whether it is a benign bone tumor or malignant. During this procedure, a sample of the tumor tissue is taken, and then histological analysis of the cells is carried out in the laboratory. There is a fine-needle biopsy, trephine biopsy, excisional and incisional biopsy, which differ in the way cells are taken.

Methods of treating bone tumors

The treatment of bone cancer in most cases requires surgery. But in modern medicine, they try to adhere to organ-preserving techniques and do without amputation. This method consists in the fact that part of the bone is removed and replaced with an endoprosthesis or bone graft. If surgery to remove a malignant bone tumor is performed on the upper limb, it can shorten the length of the arm or leg and limit its function.

In some cases, cryodestruction is performed - this is a treatment method in which low temperatures are applied and the tumor tissue is destroyed. Curettage (curettage) is also used to treat bone cancer.

After the operation, in order to eliminate the risk of recurrence of bone cancer, radiation or chemotherapy is prescribed. Such procedures may be required before surgery to improve the effectiveness of treatment. They allow you to reduce the size of the bone tumor before surgery. Radiation therapy exposes the patient to high doses of radiation, which causes side effects. Therefore, it is used when surgery is impossible or not effective enough, with recurrence of bone cancer, as a palliative treatment of patients and in some other cases.

Osteosarcomas and Ewing's sarcomas are treated with chemotherapy. Cancer treatment involves the use of special drugs that act on cancer cells. Targeted drugs can be used, which have a lower level of effect on the tissue surrounding the tumor.

If the bones are affected by cancer metastases in other organs and tissues, then the treatment of patients effective against the primary cancer is used. Chemotherapy, radiation therapy, etc.

Bisphosphonates, drugs that protect against complications (such as pathological fractures) and reduce pain, may be given to prevent bone loss due to bone cancer. Sometimes metal screws and rods are used for this. Metastases of bone cancer are also treated with radiofrequency ablation, in which the tumor and tumor cells are destroyed using a current that is applied through a needle.

As a rule, the treatment of bone cancer is carried out by a group of specialists from different fields: an oncologist, a surgeon, a specialist in chemotherapy or radiation therapy, a traumatologist and orthopedist, etc.

Secondary lesions of the spine

Metastatic lesions of the spine usually indicate the fourth stage of the disease. It significantly worsens the medical prognosis of the effectiveness of treatment.

Metastases in the bone are diagnosed with advanced cancer of the prostate, lung, breast, etc. They usually manifest themselves as lesions of the spine, pelvic bones, ribs and tubular bones of the arms or legs.

Metastases in the spine is a lesion of bone tissue by cancer cells that have spread throughout the body. They penetrate into it along with the flow of lymph or blood from the primary tumor. And since the bones are the basis of the musculoskeletal system, such a pathology in a short period of time can reduce the patient's quality of life and worsen the prognosis in general.

Metastases impair the function of osteoblasts. These cells are responsible for bone growth and reproduction of new cells, as well as helping to “recycle” cells that are no longer usable. Because of this o Metastases can cause the following types of lesions:

  • osteolytic - there is a gradual thinning of the bones, the risk of fractures increases even with light physical exertion;
  • osteoblastic - pathological growth of bone tissue.

The primary symptom of metastases is pain. At first, it is stopped by drugs, but over time it becomes more and more intense. There is a violation of the functionality of the joints. Analyzes show an excess of calcium. Compression syndrome may develop. There is compression of the spinal cord, which causes a violation of the musculoskeletal function.

Rehabilitation after bone tumor treatment

If an amputation was performed, then the lost part is replaced by a prosthesis. In this case, rehabilitation lasts faster than after organ-preserving methods of treating bone cancer. In situations without prosthetics, rehabilitation measures are required to preserve limb function.

During remission and some time after it, regular monitoring by a doctor is shown, close attention to the state of one's body. With any changes and symptoms, you should immediately be examined again.

The prognosis of the disease and survival depend on the type of bone cancer, its stage, size and location of the malignant bone tumor, etc. But in general - optimistic. 70% of patients with any malignant bone tumors survive for five years after diagnosis and treatment.

The earlier an oncological disease is detected, the higher the chances of its cure. That is why it is so important to regularly undergo scheduled medical examinations and, if you have the symptoms described above, do not delay contacting a surgeon, who, if a bone tumor is suspected, immediately sends the patient to an oncologist.

Our doctors work with modern equipment (the oncology department is equipped with MRI, CT, etc.), use new methods that have passed all clinical studies in order to make the most accurate diagnosis and apply the most effective therapy. Contact us by phone or on the website and we will call you back. Clinic K+31 is open around the clock.

Service record



Specialists

All specialists
Merkulov
Igor Alexandrovich

Deputy chief physician for oncology, oncologist

Doctor of Sciences, PhD

Lyadov
Konstantin Viktorovich

Academician, professor, Doctor of Sciences, PhD

Petrov
Dmitry Yurevich

Deputy chief physician for oncology, surgeon

PhD, Docent

Ershova
Ksenia Igorevna

Head of department, oncologist

PhD

Abashin
Sergey Yuryevich

Head of oncology projects, oncologist

Doctor of Sciences, PhD, professor

Rasner
Pavel Ilyich

Consultant in urology, urologist

Doctor of Sciences, PhD, professor

Malygin
Sergey Evgenyevich

Oncologist-mammologist, surgeon

Pshikhachev
Ahmed Mukhamedovich

Urologist, Oncologist

Doctor of Sciences, PhD

Shevchuk
Alexei Sergeyevich

Oncogynecology consultant, obstetrician-gynecologist

PhD

Chichkanova
Tatyana Vladimirovna

Oncologist-mammologist, radiologist

Katz
Ksenia Vladimirovna

Dermatovenerologist, oncologist

Udin
Oleg Ivanovich

Deputy chief physician for surgery, surgeon

PhD

Kogonia
Lali Mikhailovna

Chemotherapist

Doctor of Sciences, PhD

Ushenina
Maria Valerievna

Oncologist-chemotherapist

PhD

Volkova
Daria Mikhailovna

Head of the radiation therapy department

Gomov
Mikhail Alexandrovich

Consultant in oncogynecology, obstetrician-gynecologist

Grishin
Igor Igorevich

Obstetrician-gynecologist

Doctor of Sciences, PhD, professor

Achba
Maya Otarovna

Radiologist, ultrasound diagnostician, oncologist-mammologist

Dubinina
Yulia Nikolaevna

Head of the oncology department of antitumor drug therapy, oncologist, hematologist