Monocytes in a general blood test (MONO)
The white blood cell count includes the determination of monocytes - one of the types of white blood cells responsible for phagocytosis. This is a very important biological process when one cell absorbs another, any cell fragment, large molecular structures or immune complexes antigen-antibody. In this way, the immune system removes from the body its own dead cells, those that have lost their function, atypical cells that have arisen as a result of mutations, infectious agents (bacteria, viruses, protozoa, fungi) or their remains.
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Monocytes in the complete blood count (MONO)
Normally, the relative amount of MONO is 3-11%. An increase in this value - monocytosis - occurs with:
- Most bacterial infections
- Some viral pathologies (infectious mononucleosis, measles, rubella, flu)
- Introduction of protozoa (amebiasis, leishmaniasis, giardiasis, toxoplasmosis)
- Sarcoidosis, nonspecific ulcerative colitis
- Autoimmune processes
- Systemic diseases of connective tissue
- Acute monocytic leukemia, lymphoma, myeloma
A decrease in the level (monocytopenia) usually does not have specific causes and is associated with the suppression of hematopoiesis in bone marrow against the background of:
- Various deficiency states (iron, B vitamins, folic acid)
- Myelosuppression (chemoradiation therapy)
- Immunosuppression (glucocorticoid treatment, HIV)
- Severe condition of the body with sepsis, multiple organ failure
- Poisoning
- Severe forms of leukemia
Monocyte testing should be performed with each general blood test, which will allow timely detection of diseases with a long-latent clinical picture and timely initiation of treatment.
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