Biorevitalization Plinest (Plinest)
Age-related changes are inevitable for any person. After 30 years, expression lines, circles and bags under the eyes appear. From about 40-45 years old, women's facial shape changes, ptosis, double chin, and pigmentation appear. To slow down the natural aging process, innovative cosmetic procedures are carried out. The most popular methods include biorevitalization, mesotherapy and bioreparation. Their main goal is to restore the intercellular matrix of the skin and activate metabolic processes. Among the innovative methods of skin biorevitalization in Moscow clinics, the leader is polynucleotide therapy using the drug Plinest.
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Principle of action, indications,
contraindications and advantages
How does polynucleotide treatment work?
Polynucleotides are not foreign substances that accumulate in the skin and form their framework. The principle of operation of the substance is contact with blood fibroblasts in the subcutaneous layers and activation of their work. Essentially, it is a catalyst that stimulates natural metabolic processes in cells and triggers cellular regeneration.
Polynucleotide therapy has become an innovative method of rejuvenation and prevention of aging. Plinest is the only original product today containing polydeoxyribonucleotide. The need for polynucleotide therapy is caused by the peculiarities of the skin life cycle. Under the influence of age-related changes or environmental factors, the processes of dividing new cells and removing old ones slow down. As a result, defects appear - age spots, wrinkles, creases, dry skin.
Reduced production of collagen and elastin due to hormonal changes in the body causes ptosis and skin aging. Polynucleotide therapy in the process of biorevitalization solves the main problem - it stimulates cellular regeneration, activates the process of cell division of collagen and elastin, and participates in the construction of a new subcutaneous framework.
The use of polynucleotides makes it possible:
- Increase the proliferation of fibroblasts, increase the production of collagen fibers by 60%
- Strengthen angiogenesis of the skin - stimulate the appearance of new subcutaneous capillaries, improve oxygenation
- Activate fibronectin protein synthesis by 37%, increase skin elasticity
- Influence adenosine A2A receptors to reduce inflammatory factors
- Protect cells from the damaging effects of ultraviolet radiation
Also, therapy with polynucleotides allows you to remove free radicals from the skin and increase immune protection from the negative influence of the external environment - dust, dirt, solar radiation.
The procedure differs from standard biorevitalization in that ready-made nourishing and moisturizing components or cocktails are not introduced into the skin. The technology of stimulation and activation of the body’s own forces is used for accelerated regeneration of the skin. Therefore, the procedure is also often called bioreparation, that is, a biological method of reconstructing skin problems from the inside.
Composition biorevitalizer
The composition of Plinest preparations differs in the concentration of the main substance:
- Plinest - polynucleotides 20 mg/ml
- Plinest fast - polynucleotides 7.5 mg/ml
- Plinest light - polynucleotides 2 mg/ml
Excipients: monobasic and dibasic sodium phosphate dihydrate, purified water, sodium chloride. The drug is packaged in syringes of 2 ml of isotonic gel. The acidity of the substance is pH 7.2.
Indications for biorevitalization Plinest
Polynucleotide therapy is indicated for:
- Prevention of skin aging
- Elimination of age-related changes (wrinkles, ptosis, sagging, dryness) and body (stretch marks)
- Prevention and treatment of alopecia
- Elimination of hyperpigmentation
- Face oval correction
Biorevitalization is carried out to correct the skin of the face, neck, décolleté, and hands. The procedure is also provided for the scalp and problem areas of the body.
Depending on the type of problem, the doctor selects the type of drug Plinest.
For example, Plinest fast biorevitalization is used to prevent and treat baldness or strengthen hair. Suitable for young skin and delicate areas around the eyes.
Plinest light is used to moisturize the skin before other cosmetic procedures and to consolidate the results. The Plinest line with the maximum concentration of the active substance is suitable for combating pronounced signs of aging for deep tissue regeneration.
The biorevitalization procedure with Plinest is used as a preparatory stage before Botox injections, after cosmetic procedures (laser peeling, hardware facelift), plastic surgeries (blepharoplasty).
Contraindications to biorevitalization
Injections with drugs, including Plinest, are not recommended for people under 18 years of age, during pregnancy or lactation. Manipulation is not performed on patients with:
- Oncology
- Exacerbation of infectious diseases
- HIV/AIDS
- Damage to the skin at the procedure sites
- Individual intolerance to the components of the drug
- Autoimmune diseases in the stage of decompensation
- Blood clotting disorder
The possibility of using the drug, as well as the procedure technique, is determined by a dermatologist-cosmetologist during a consultation.
Benefits of Plinest
The drugs differ:
- High density, which allows you to prolong the effect of the procedure
- Hypoallergenic, does not require preliminary testing
- Versatility - suitable for all skin types of face and body
- High quality, confirmed by the company’s reputation
- Directed action - can be used clearly for specific areas without affecting surrounding tissue
The drug activates blood circulation and tissue oxygenation and is compatible with all cosmetic products.
General information about the procedure
Types of biorevitalizants Plinest
The manufacturer produces three lines of drugs for biorevitalization.
| Property | Plinest | Plinest fast | Plinest light |
|---|---|---|---|
| Main purpose |
|
|
|
| Patient age | Over 45 years | Over 30 years | 20-25 years |
| Area of application | Face, neck, décolleté, body, hands | Delicate areas of the body and face, scalp | Face, neck, décolleté, arms, legs |
All Plinest preparations are recommended to be used in a course of 3-5 biorevitalization procedures with a break of 2-3 weeks. For To maintain the result, the course can be repeated 3 times a year.
Answers to popular questions
Which Plinest drug should I choose to prevent skin aging?
How to care for your skin after biorevitalization?
Will Plinest Fast help with hair loss?
About the Department of Aesthetic Medicine K+31
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Features of the drug Plinest
Modern injection cosmetology helps improve skin quality and prolong youth, achieving lasting results. Plinest is an innovative development of the biopharmaceutical company Mastelli (Italy), which has no analogues in the world. The drug Plinest is intended for performing biorevitalization procedures, for the treatment and prevention of baldness in women or men.
The peculiarity of the drug is its unique composition. Unlike conventional biorevitalizants, it does not contain hyaluronic acid. Plinest is based on polynucleotides - fibroblast stimulators. These skin cells are responsible for producing its own collagen, elastin and hyaluronic acid.
Mastelli has patented the “SALVAGE” technology for producing polynucleotides from animal DNA fragments. After lengthy laboratory studies, a biomaterial was selected that corresponds to the DNA of human cells and has a high percentage of compatibility.
Plinest is particularly viscous. This allows it to be effectively used for biorevitalization with a prolonged action, combined with other methods of injection cosmetology, enhancing their results.
The Plinest line includes drugs of different concentrations, which allows you to smoothly vary the choice of procedures based on the patient’s age, existing cosmetic problem and skin condition.