ASIT therapy for children

How is ASIT performed

Treatment of allergic manifestations is preceded by a thorough diagnosis to identify irritants responsible for the formation of a specific immune response. To do this, a series of special skin tests are performed or tests are taken to determine the level of immunoglobulin E in the blood.

ASIT for allergies in children is performed using one of the following methods:

• Injection, involving the subcutaneous injection of drugs containing allergens into the lower third of the shoulder.
• Oral for oral administration in the form of drops, tablets or capsules.
• Sublingual, when the patient first holds the allergen in the mouth for several minutes and then swallows or spits it out.
• Intranasal, i.e. a water-soluble or powdered irritant is introduced with a pipette through the nasal passages.

Allergy shots for children are given in a doctor's office. After the vaccine is administered, the patient remains under observation for some time to assess the immune response. Treatment by other methods can be carried out at home, but strictly as prescribed by a doctor under the supervision of parents. Sublingual ASIT is preferable for small allergy sufferers, because Unlike injections, it is painless and does not cause fear.

Method of treatment

The ASIT allergy treatment method is based on the parenteral principle. After administration of the initial dose, the number of causally significant allergens is gradually increased until maximum values are reached, administering the medicine every day or alternating with daily and then at long intervals, but not more than 7-10 days. Then maintenance therapy is carried out to stabilize the achieved dose at intervals of two weeks. Depending on the type of medicinal allergens, their concentration and frequency of administration are adjusted by the attending physician according to current dynamic indicators.

The sublingual method of ASIT differs from the injection method in higher allergodoses, causing an increase in the amount of immunoglobulins in the blood during exposure to allergens during the flowering period. Sublingual immunotherapy has been proven to be noticeably effective after 2 years of hay fever treatment. The preparations used contain a seasonal mixture of allergens characteristic of a certain time of year.

In the event of an allergic reaction to stinging insect bites, ASIT involves parenteral medication from the beginning of winter until summer, and then maintenance vaccination until mid-autumn. The achieved effectiveness is about 95% with continuous 3-5 year treatment.