In January 2022, the National Cancer Network (NCCN) made a number of significant additions to the recommendations for radiation therapy for rectal cancer, which are important not only for specialists, but also for patients:
Patients of childbearing age should be counseled about the consequences of premature menopause and consideration should be given to hormone replacement therapy with specialized specialists.
Patients of childbearing age should be informed that with radiation therapy involving the uterus, the risk of preterm birth is very high in the future.
Patients should be counseled about sexual dysfunction, potential low testosterone levels, and risks of infertility, and provided information about a sperm bank or an egg or ovarian tissue bank, as appropriate, prior to initiating treatment.
Also, the possibility of radiotherapy or brachytherapy shortly after surgery, before adjuvant chemotherapy, was removed from the recommendations.